As I’ve been cataloguing the Rosin Institute’s offprints, I came across a very interesting item by Dr. Grahame Bulfield, the former director and chief executive of the Roslin Institute and vice-principal, University of Edinburgh and who is also consulting with and providing us with his considerable knowledge and insight of genetics in Edinburgh on the Towards Dolly project. This brief abstract of the paper, ‘From gene to trait: opening the black box’ found in the Journal of Endocrinology, Volume 140, Supplement, Abstract S18, 1994 (GB 237 Coll-1362/4/329):
Or here: http://joe.endocrinology-journals.org/content/140/3_Suppl/S18.full.pdf
As you can see, he mentions that while there was little success in 1994 of manipulating ‘commercially important traits’ of various animals there was the increasing potential for success by using the research gathered from the Human Genome Mapping Project to establish similar projects for various animals. There are many other papers in the Roslin Institute offprints that discuss various aspects of research on transgenic animals that I’ve catalogued and you’ll be able to search for them once the online catalogue is available in the near future.