{"id":842,"date":"2013-10-07T10:00:37","date_gmt":"2013-10-07T10:00:37","guid":{"rendered":"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/?p=842"},"modified":"2013-10-07T10:00:37","modified_gmt":"2013-10-07T10:00:37","slug":"from-gene-to-trait-opening-the-black-box","status":"publish","type":"post","link":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/2013\/10\/07\/from-gene-to-trait-opening-the-black-box\/","title":{"rendered":"From gene to trait: opening the black box"},"content":{"rendered":"<p>As I\u2019ve been cataloguing the Rosin Institute\u2019s offprints, I came across a very interesting item by Dr. Grahame Bulfield, the former director and chief executive of the Roslin Institute and vice-principal, University of Edinburgh and who is also consulting with and providing us with his considerable knowledge and insight of genetics in Edinburgh on the Towards Dolly project.\u00a0 This brief abstract of the paper, \u2018From gene to trait: opening the black box\u2019 found in the <i>Journal of Endocrinology<\/i>, Volume 140, Supplement, Abstract S18, 1994 (GB 237 Coll-1362\/4\/329):<\/p>\n<p><a href=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-medium wp-image-843\" alt=\"Bulfied Gene to Trait\" src=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146-300x225.jpg\" width=\"300\" height=\"225\" srcset=\"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146-300x225.jpg 300w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146-1024x768.jpg 1024w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146-400x300.jpg 400w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2013\/10\/IMG_4146.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>Or here: <a href=\"http:\/\/joe.endocrinology-journals.org\/content\/140\/3_Suppl\/S18.full.pdf\">http:\/\/joe.endocrinology-journals.org\/content\/140\/3_Suppl\/S18.full.pdf<\/a><\/p>\n<p>As you can see, he mentions that while there was little success in 1994 of manipulating \u2018commercially important traits\u2019 of various animals there was the increasing potential for success by using the research gathered from the Human Genome Mapping Project to establish similar projects for various animals. There are many other papers in the Roslin Institute offprints that discuss various aspects of research on transgenic animals that I\u2019ve catalogued and you\u2019ll be able to search for them once the online catalogue is available in the near future.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As I\u2019ve been cataloguing the Rosin Institute\u2019s offprints, I came across a very interesting item by Dr. Grahame Bulfield, the former director and chief executive of the Roslin Institute and vice-principal, University of Edinburgh and who is also consulting with &hellip; <a href=\"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/2013\/10\/07\/from-gene-to-trait-opening-the-black-box\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":35,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[3,116],"tags":[122,90,121],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p40Aqf-dA","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts\/842"}],"collection":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/users\/35"}],"replies":[{"embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/comments?post=842"}],"version-history":[{"count":2,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts\/842\/revisions"}],"predecessor-version":[{"id":845,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts\/842\/revisions\/845"}],"wp:attachment":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/media?parent=842"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/categories?post=842"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/tags?post=842"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}