{"id":200,"date":"2012-06-25T13:51:22","date_gmt":"2012-06-25T13:51:22","guid":{"rendered":"http:\/\/towardsdolly.wordpress.com\/?p=200"},"modified":"2012-06-25T13:51:22","modified_gmt":"2012-06-25T13:51:22","slug":"transgenic-sheep-genetic-engineering-at-abro","status":"publish","type":"post","link":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/2012\/06\/25\/transgenic-sheep-genetic-engineering-at-abro\/","title":{"rendered":"Transgenic sheep &#8211; genetic engineering at ABRO"},"content":{"rendered":"<p>Since this is called the \u2018Towards Dolly\u2019 project after Dolly, the cloned sheep, created by scientists at the Roslin Institute, I was excited to find this article \u2018Germline Manipulation of <a href=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"size-medium wp-image-201 alignleft\" title=\"ImmunogeneticsABROReport1986v2\" src=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2.jpg?w=225\" alt=\"\" width=\"225\" height=\"300\" srcset=\"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2.jpg 1200w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2-225x300.jpg 225w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2-768x1024.jpg 768w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v2-624x832.jpg 624w\" sizes=\"(max-width: 225px) 100vw, 225px\" \/><\/a>Livestock\u2019 by \u2018research workers\u2019:\u00a0 J. O. Bishop, A. L. Archibald, A. J. Clark, R. F. Lathe, J. P. Simons, and I. Wilmut on creating transgenic sheep in the 1986 Annual Report from the Animal Breeding Research Organisation. The article discusses the various new methods of changing animal genotypes that were recently developed. Also, how \u2018a gene can be isolated from an animal or from man, altered in the laboratory, and introduced into individuals of the same or a different species of animal (usually a mouse) where it becomes incorporated into the genome and usually breeds true. Animals which have received genes in this way are said to be \u2018transgenic\u2019.\u2019 Amongst the topics mentioned are: gene expression, cloned genes, focusing on mammary glands, the choice of sheep breed, proteins of commercial value, altering the composition of milk and ideas for the future.<a href=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3.jpg\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-202 alignright\" title=\"ImmunogeneticsABROReport1986v3\" src=\"http:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3.jpg?w=211\" alt=\"\" width=\"211\" height=\"300\" srcset=\"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3.jpg 973w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3-211x300.jpg 211w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3-720x1024.jpg 720w, https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/files\/2012\/06\/immunogeneticsabroreport1986v3-624x886.jpg 624w\" sizes=\"(max-width: 211px) 100vw, 211px\" \/><\/a><\/p>\n<p>I love the simplicity of the diagram showing the procedure to produce transgenic sheep!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Since this is called the \u2018Towards Dolly\u2019 project after Dolly, the cloned sheep, created by scientists at the Roslin Institute, I was excited to find this article \u2018Germline Manipulation of Livestock\u2019 by \u2018research workers\u2019:\u00a0 J. O. Bishop, A. L. Archibald, &hellip; <a href=\"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/2012\/06\/25\/transgenic-sheep-genetic-engineering-at-abro\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":31,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[3],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p40Aqf-3e","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts\/200"}],"collection":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/users\/31"}],"replies":[{"embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/comments?post=200"}],"version-history":[{"count":0,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/posts\/200\/revisions"}],"wp:attachment":[{"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/media?parent=200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/categories?post=200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/libraryblogs.is.ed.ac.uk\/towardsdolly\/wp-json\/wp\/v2\/tags?post=200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}